At Cape Fear Physical Medicine and Rehab, we offer GLP-1 receptor agonists like Wegovy , which are used for weight management in adults who are overweight or obese
GLP-1RAs alleviate liver injury by inhibiting hepatocyte apoptosis and promoting the TFEB-dependent transcription of lysosome-related genes, which stimulates hepatocyte autophagy to prevent lipid accumulation (Elsiad et al., 2025
2013;98(7):E116372
This testing enables individuals to make knowledgeable choices regarding their health, family planning, and lifestyle by considering genetic predispositions and ancestry
Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations