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Tirzepatida es un agonista del receptor de GIP (polipptido insulinotrpico dependiente de glucosa) y del receptor de GLP-1 (pptido similar al glucagn-1) de administracin semanal
And so the answer was clear
However, their effects in MASLD remain underexplored
These resistance-associated genes also overlapped with those identified in an additional genetic screen seeking to identify drivers of estrogen-independence - with CSK also as a shared top hit suggesting that the identified genes are relevant for general endocrine resistance (and perhaps G1 arrest), rather than representing a giredestrant-specific resistance program 36
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