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Wong led a follow-up study that found semaglutide acts directly on GLP-1 receptors in the brain in a way that dampens inflammation throughout the body, even though GLP-1 receptors havent been found widely on immune cells outside the gut

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Consequently, GLP-1-RAs have been shown to promote cell proliferation, exert anti-inflammatory effects, improve cardiovascular health, and may help to preserve neurological functions [160]

The FDA has expressed many concerns with these knockoffs including improper storage, dosing errors, questionable sourcing of active pharmaceutical ingredients, and misleading advertising practices

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