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A crucial intermediate cytoplasmic protein substrate for insulin receptor kinase is the insulin receptor substrate-1 (IRS-1), a peptide with multiple potential tyrosine phosphorylation sites within its molecule
GIP (Glucose-Dependent Insulinotropic Polypeptide) Receptors enhance insulin secretion and appear to improve fat metabolism
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Once the NDA is approved, the sponsor can sell the new drug in the US
[DOI] [PubMed] [Google Scholar] 93.Gallwitz B., Witt M., Flsch U.R., Creutzfeldt W., Schmidt W.E
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