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It was initially intended for patients with genetic disorders such as xeroderma pigmentosum, who suffer from extreme UV sensitivity

In January 2025, Merck also received expanded approval in China for Gardasil in males aged nine to 26 years

These findings strongly suggest that COF platforms-whether in their native form or through bioinspired modifications-possess unique and broadly applicable advantages in reshaping the tumor immune architecture and eliciting the most effective antitumor immune responses, laying a solid theoretical foundation for their clinical translation

These processes are closely interrelated, amplifying each other and contributing to long-term neuronal damage and neurodegeneration