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FDA-Approved Clinical Indications Primary Indication Management of Resistant Anemia and Muscle Cramps: Specifically indicated for the treatment of carnitine deficiency in dialysis patients to improve the response to Erythropoiesis-Stimulating Agents (ESAs) in cases of resistant anemia and to reduce the frequency and severity of intradialytic skeletal muscle cramps

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31 The overall TRIUMPH1 and TRIUMPH2 sample sizes provide at least 90% power to detect clinically meaningful weight reduction with retatrutide at 9 and 12 mg doses versus placebo on percent change in body weight, assuming each dose is analysed separately in parallel using a 2sample t test at a 2sided significance level of 0.0125

Therefore, knowledge of the LDL-C reduction levels for specific doses and formulations is so important