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The phosphorylated form of NAD + , NADP/NADPH, parallels NAD + /NADH by functioning as a redox coenzyme in the pentose phosphate pathway, generation of acetyl coenzyme A (acetyl-CoA) for lipid and cholesterol biosynthesis, and in the glutathione and thioredoxin antioxidant systems 4,5,8,9

The most severe risks include promoting the growth of existing cancers, severe hypoglycemia (low blood sugar), and acromegaly (abnormal bone and organ growth)

Genazzani, A

Anemia caused by a defect on chromosome 16, which codes for -globin, is called -thalassemia and -thalassemia is caused by a defect on chromosome 11, which codes for -globin