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Withdrawal symptoms, ranging from a return of uncomfortable psychological symptoms to physical manifestations such as nausea and diarrhea, may occur when the drugs are removed from the bloodstream

To improve corneal residence time, penetration, and targeted administration of natural compounds, future research should use in situ gels, nanoparticle-based carriers (liposomes, polymeric NPs), and contact lens drug delivery

This design allows for easy swallowing and ensures a precise dosage of the active ingredients, thereby facilitating better absorption and utilization of the medication

It will reduce the melanin, which results in a reduction of black patches and pigmentation

Borchert A, Kalms J, Roth SR, Rademacher M, Schmidt A, Holzhutter H-G et al (2018) Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction