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Most proteins are not stable in acidic pH, so you will want to adjust your pH back to the desired value using a concentrated base such as sodium hydroxide before using your elution buffer

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Distinct pathological features, including differences between glomerular and tubular injury in the kidney, lobular and periportal inflammation in the liver, and depot-specific inflammatory responses in adipose tissue, complicate the design of broadly effective therapeutic strategies [517519]

J Child Neurol 1991, 6: 7-14

Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice