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Some studies indicate that l-citrulline supplementation may support exercise recovery and perceived muscle soreness following intense exercise, depending on study design and training context

1 A few key points for clinicians: Short half-life (1012 min): This quick clearance supports physiologic GH pulses rather than continuous stimulation. Preserved feedback loops: IGF-1 and somatostatin feedback acts to keep GH levels within physiologic norms

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