Originally developed for the treatment of type 2 diabetes mellitus, these agentsincluding semaglutide and tirzepatidehave demonstrated substantial efficacy in promoting weight loss and are increasingly reshaping therapeutic strategies for obesity, cardiovascular and kidney disease, and potentially substance use disorders.[1,2] Historically, paradigm-shifting therapeutics have periodically redefined clinical practice
[DOI] [PubMed] [Google Scholar] 118.Wattanathorn J., Chonpathompikunlert P., Muchimapura S., Priprem A., Tankamnerdthai O
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4.3 Multiple sclerosis MS is a systemic AID of unknown etiology, characterized by immune dysregulation, skin and visceral organ fibrosis, and vascular dysfunction, which are thought to be related to the pathogenesis of MS (161163)
Stopping semaglutide, however, leads to significant weight regain