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Common signs and symptoms include [2, 4]: Weight loss Anxiety and irritability Increased heart rate Fatigue Tremors Sensitivity to heat Enlarged thyroid gland (swollen neck) Irregular periods Eye pain and redness Swollen and protruded eyeballs (Graves ophthalmopathy) Thick, red skin on the shins or feet (Graves dermopathy) Dermopathy (skin disease) These symptoms are not unique, many other conditions can cause them