Nrf2 activation regulates antioxidant responses to modify cellular redox states from predominantly pro-oxidant to antioxidant, and, in an antioxidant environment, macrophage phenotypes shift from M1 pro-inflammatory to M2 anti-inflammatory, reducing the probability of cytokine storms, ARDS, and lethality (Tan et al., 2016
This includes cardiovascular disease, type 2 diabetes, high blood pressure, high cholesterol, thyroid conditions, pancreatitis, kidney disease, liver disease, gallbladder problems, and mental health conditions
doi: 10.2478/rjim-2019-0003 194 ZobelEHRipaRSvon ScholtenBJRotbain CurovicVKjaerAHansenTWet al
Bioavailability is the measure of how much of a nutrient actually enters your bloodstream so your body can use it
[9] Wicklow B, Retnakaran R