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Eating slowly and chewing thoroughly allows more time for GLP-1 to signal satiety to your brain, potentially reducing overall food intake

The same study found that GLP-1 drugs also reduced the risk of addiction to substances like alcohol, cannabis, stimulants, and opioids

23 Factors such as convenience (e.g., frequency of administration) and tolerability are certainly important, but the choice of agent may also be determined by the individualized glycemic needs of the patient

The NTS is the main source of endogenous GLP-1 within the brain (Holt et al., 2019)

The effects of semaglutide were consistent in those using renin-angiotensin system (RAS) blockers and SGLT2 inhibition compared with those not on these therapies