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The forceful agitation can shear the delicate amino acid chains, a process called denaturation, which destroys the peptides biological activity and renders it useless for research

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Subjects who developed NOD in the 3 years after statin initiation were identified and recruited, with diabetes defined as two or more of the following diagnostic elements: (1) FG 126 mg/dL, (2) diabetes ICD9 code, and/or (3) prescription of a glucose lowering drug (Supplementary Data 2)

Patient-reported experiences vary considerably