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In the mitochondria, 4050% of CoQ 10 lies in the inner membrane and exists in one of three states: fully oxidized (ubiquinone, also known as Q or ubidecarenone), partially reduced (semiubiquinone), and fully reduced (ubiquinol, CoQH 2 ) 8

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In AD, GSH depletion impacts microglia function and reduces -amyloid clearance