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PACSIN2 encodes a lipid-binding protein that interacts with Rac1, the molecular target of thiopurines ( MOCOS, MAT1A, MAT2A , and TYMS , though not directly involved in thiopurine metabolism, have also been implicated in thiopurine resistance because of their TPMT activity-altering action (Karas-Kuzelicki et al., 2010

Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus

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