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These responders have exhibited an increase in the level of CD8 + (IFN + ) T cells, CD4 + (IFN + ) T cells and CD8 + /Treg ratio compared to the non-responders of anti-PD-1 treatment

From there, they recommend a starting dose and create a custom plan for gradual dose adjustments

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Data availability The research team gathered the data described in this manuscript during the study period