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Nonetheless, further investigations are warranted to fully elucidate the underlying mechanisms and optimize the treatment protocol for maximal clinical benefit

Common mild effects: Temporary flushing or warmth at infusion site (typically brief) Mild headache in some patients at higher doses Rare nausea Important clinical considerations: Patients with asthma should be evaluated prior to IV glutathione because inhaled glutathione has been associated with bronchospasm in some asthmatic individuals

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Chronic activation of these glial cells drives neuroinflammatory processes that accelerate neurodegeneration, making their modulation a critical therapeutic target

World Journal of Gastroenterology: WJG, 20 (5), 1165-1179