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Specific attention is given to understanding the inconsistencies in the prospective studies

We note the measure developer conducted testing to examine the need for risk adjustment to the measure for a set of factors such as patients self-reported health status, history of procedures, age, and education, and found there was not a significant relationship between the adjusted and unadjusted measure scores

The effect of a subnormal vitamin B-6 status on homocysteine metabolism

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Statistical analyses were based on historical controls