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Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a beta-arrestin-1 dependent manner

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Interestingly, the expression of Beclin-1 downregulates the estrogen signal, which is beneficial to overcoming the resistance to tamoxifen (John et al., 2008)

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Caspase-dependent apoptosis is also observed in leukemia, prostate, glioma and osteosarcoma cells following delphinidin treatment (Hou et al., 2003