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The use of a molecular connectomics approach made it possible to identify a GLP-1-sensitive neural network responsible for feeling full and associated with neurons of the arcuate nucleus [14]

These include the gut-derived hormones, such as the potent incretins glucagon-like polypeptide-1 (GLP-1) and gastric inhibitory peptide (GIP) and the -cell hormone amylin

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While Retatrutide is not yet available, its potential is already making waves