semaglutide histamine Antihistamines in MCAS aren't a cure. They don't “fix” mast cells — they Use of new diet drugs

The exact mechanisms that are preventing GLP-1 drugs from having an effect still need to be investigated

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References: Heyder NA, Kleinau G, Speck D, Schmidt A, Paisdzior S, Szczepek M, Bauer B, Koch A, Gallandi M, Kwiatkowski D, Brger J, Mielke T, Beck-Sickinger AG, Hildebrand PW, Spahn CMT, Hilger D, Schacherl M, Biebermann H, Hilal T, Khnen P, Kobilka BK, Scheerer P

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Inside cells, the endoplasmic reticulum (ER) is responsible for protein folding and quality control