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Information Collection Burden Estimate for the Adoption of the Emergency Care Access & Timeliness eCQM With Voluntary Reporting for the CY 2027 Reporting Period, Followed by Mandatory Reporting Beginning With the CY 2028 Reporting Period/CY 2030 Payment Determination As discussed in section XV.B.1

When melanin production increases or becomes irregular, the skin can appear darker or develop hyperpigmentation

309 Kallidinogenase, another microcirculation enhancer, increases capillary blood flow by generating bradykinin, leading to vasodilation and enhanced tissue perfusion

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10.1111/j.1365-3040.2011.02355.x 76 RizhskyL.Hallak-HerrE.Van BreusegemF.RachmilevitchS.BarrJ