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PYY is another candidate for the short-term control of food intake (64, 65) that originates from the L-cells in the ileal and colon mucosa following stimulation by feeding, particularly when ingested nutrients, namely fatty acids, reach the distal portion of the small bowel and colon (66)

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Proc Natl Acad Sci U S A (2007) 104(7):246570

[DOI] [PMC free article] [PubMed] [Google Scholar] 157.Richardson J.R., Quan Y., Sherer T.B., Greenamyre J.T., Miller G.W

This conservative approach maintains the option to pause or discontinue if complications arise, while keeping treatment affordable and accessible across all 50 states without insurance requirements