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Despite these findings, the existing limitations of the studies mentioned make it impossible to reach a conclusive verdict at this time [7, 145, 147, 148]

Excess glutamate or poor glutamate clearance can overstimulate brain circuits involved in error detection, intrusive thoughts, compulsive urges, anxiety, and insomnia

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10.3389/fphar.2018.01383 98 KharelS.OjhaR

The long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and proton pump inhibitors (PPIs) has numerous documented negative repercussions, including increased toxicity and elevated ROS levels, which may be reduced with GHS