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Practical considerations for use : Dosing : Research studies typically use 500 mg two to three times daily with meals, though there is no officially approved dosing regimen
Like nausea, it is most common during the early phase of treatment or after dose increases and typically improves with time
Missing one application should not drastically affect results, but consistency is key
Importantly, the prevalence of adverse effects does not appear to differ from that observed in patients with T2DM treated with GLP-1 RAs
Rapid weight loss, dehydration, and changes in fat metabolism can temporarily stress the liver in some cases
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