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doi: 10.1186/s13075-018-1582-3 86 SimonLS

10.1093/jjco/hyf035 [DOI] [PubMed] [Google Scholar] Baric M., Sever A

The choline utilization (cut) gene cluster was first identified by Balskus and colleagues, which transforms choline into TMA via gene products of cutC and cutD ( FIGURE 3 The first choline-TMA lyase inhibitor, DMB, was identified by Wang and colleagues, which is shown to non-lethally inhibit distinct microbial TMA lyases, and reduce TMAO levels in mice fed a high-choline or L-carnitine diet ( Compared to cutC/D, the identification of CntA/B inhibitor is relatively lagging

Nucleic Acids Res 47 , D711D715 (2019)