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But this FDA rule only applies to identical or nearly identical versions of a commercially available drug

Notably, non-internalized NPs like pristine SiO 2 NPs [452] and LaVO 4 :Eu 3+ NPs [459] can still trigger eryptosis, relying on Ca 2+ signaling, which can be mediated by their direct influence on Piezo1 channels

MAHT at 4 mg produced a mild response

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