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Klass and Dr

These symptoms are primarily due to the mode of action of GLP-1 RAs on the gut, as a GLP-1 may directly or indirectly regulate electrolyte and fluid homeostasis by influencing feeding and drinking behavior as well as electrolyte transport in the kidneys and gastrointestinal tract [25]

As liraglutide and semaglutide induced stronger HbA1c reductions versus placebo then lixisenatide, it was important that the authors showed in reply to a letter to the editor that the anti-albuminuric effects were independent of glucose-lowering in post-hoc analyses

Cork, S

But while the benefits of GLP-1 receptor agonists for the treatment of type 2 diabetes, obesity and cardiovascular disease are well known, their impact on chronic kidney disease (CKD) has been less certain