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It is therefore recommended that administration of the oral formulation of semaglutide should be in the fasting state [27,28,29]

Zepbound is the brand name specifically approved for chronic weight management, while Mounjaro is the brand name for the version approved for Type 2 diabetes

Pharmacologic Approaches to Glycemic Treatment: Standards of Care in Diabetes2025

However, the decision should always be made with a licensed healthcare provider, based on your history, your response to treatment, and your long-term health goals

If you are struggling with severe post-injection diarrhea, discussing dose splitting with a healthcare provider may be worthwhile