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Mechanism of Action (How DSIP Works) CNS Penetration: Crosses the blood-brain barrier, exerting central effects on sleep regulation [Graf 1981]

Chen K, Maines MD

Finally, transfected neurons were immunostained for presynaptic markers, VGLUT1 and synapsin, and postsynaptic marker, PSD-95, to assess functional synapse formation

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It is also notable that Zip14 regulates inflammatory signaling in adipocyte hypertrophy [129]