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In parallel, extracellular acidification facilitates matrix degradation and remodeling, enhances the invasive and metastatic potential of tumor cells, and promotes angiogenesis by activating pro-angiogenic signaling pathways, collectively providing sustained support for malignant transformation [55, 56]

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The regulation of glucose and lipid homeostasis via PLTP as a mediator of BATliver communication

Glutathione S -transferase enzymes catalyze its conjugation to lipophilic xenobiotics, facilitating their excretion or further metabolism