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Cortisol Levels: Chronically elevated stress hormone (cortisol) promotes fat storage and actively stimulates the appetite centers in the brain continuously

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International Journal of Colorectal Disease, 29(12), 1527-1534

Behav Sleep Med 12(4):290306 Onaolapo JO et al (2016) Caffeine and sleep-deprivation mediated changes in open-field behaviours, stress response and antioxidant status in mice

While GLP-1 receptor agonists were developed to treat type 2 diabetes, many have demonstrated significant weight loss or weight maintenance effects