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Altogether, these data support the use of antioxidants (AOX) to reduce the deleterious impact of ROS on skin and prevent hyperpigmentation

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IschemiaReperfusion or Hypoxic Injury Models In research models of ischemic insult (e.g., engineered tissue constructs under oxygen deprivation), the blend may be relevant to evaluations of its potential to rescue microvasculature, reduce necrosis spread, or promote regenerative infiltration when reperfusion is restored

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Reactive oxygen species and cellularstress signaling. Biochem J