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While sommarutide is undoubtedly an exciting potential treatment option, there is still a lack of clear clinical data on the mechanism of action of GLP-1 agonists in NASH, such as whether GLP-1 agonists have a direct, independent role in improving NASH, or simply by improving body weight, insulin resistance, and so on

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For health plans including these drugs on their prescription drug formularies, utilization management tools, like prior authorization and step therapy, can be used to allow medically indicated access to the drugs while controlling costs by tying coverage of the drugs to specific clinical and treatment criteria

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Some celebrities have spoken about using these drugs, while others have denied it