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It also remains unclear whether improvements are driven purely by biomechanical changes from weight loss or whether cardiometabolic mechanisms contribute independently, potentially offering disease-modifying effects or benefits through intra-articular delivery

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Allulose is also permitted in Japan, Mexico, Singapore, and South Korea

4 These startling figures have severe implications for public health, with obese individuals at increased risk of heart disease, stroke, type 2 diabetes, and certain types of cancer