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Trulicity (dulaglutide) injection, for subcutaneous use: prescribing information

These bacteria live in your gut lining and produce short-chain fatty acids

Abbreviations BBB: Blood-brain barrier CGRP: Calcitonin gene-related peptide CM: Chronic migraine CNS: Central nervous system CSD: Cortical spreading depression DMEM: Dulbeccos modified Eagles medium FBS: Foetal bovine serum GLP-1R: Glucagon-like peptide-1 receptor IGF-1: Insulin-like growth factor-1 IS: Inflammatory soup LPS: Lipopolysaccharide NTG: Nitroglycerin PI3K: Phosphoinositide 3-kinase PKA: Protein kinase A PMSF: Phenylmethylsulfonyl fluoride RT: Room temperature TNC: Trigeminal nucleus caudalis References May A, Schulte LH (2016) Chronic migraine: risk factors, mechanisms and treatment

Navigating Side Effects Through Dietary Adjustments If you experience common side effects like nausea or constipation, specific dietary strategies can help: For Nausea: Opt for bland, low-fat foods like crackers, toast, rice, and broth-based soups

doi: 10.1016/j.biopsych.2017.11.018 60