doi: 10.3390/ijms24044062 37 RaiG
*Correspondence: Youxin Chen, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
Recommendations for the assessment of carotid arterial plaque by ultrasound for the characterization of atherosclerosis and evaluation of cardiovascular risk: from the American Society of Echocardiography
Chronic low-grade inflammation is a common pathological feature of both: metabolic disturbances in patients with DM induce the release of peripheral inflammatory factors, and these inflammatory factors pass through the compromised BBB into the central nervous system (CNS), activating microglia and astrocytes and triggering a neuroinflammatory cascade response, which in turn promotes A deposition in AD and tau protein hyperphosphorylation (Sebastian Monasor et al., 2020
No absorption is required, so plasma levels are independent of such factors as gastrointestinal (GI) absorption and adequate skin or muscle perfusion
