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The approved population is not a gut-health population: In the pivotal trial the average patient had 77 cm of remaining small intestine against a normal length of roughly 6 metres, had been dependent on intravenous nutrition for a mean of 6 years , and in 44% of cases had no colon in continuity [2]

GIPR activation potentiates glucose-dependent insulin release and has more recently been shown to modulate adipose-tissue lipid handling and central appetite pathways

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Growth hormone affects practically every bodily tissue and organ.6 Its chiefly responsible for facilitating physical growth and metabolism, the process of converting food into usable energy.7 The metabolic effects of growth hormone are due to its stimulating effect on the production of insulin-like growth factor-1 (IGF-1), which is important for regulating body composition