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Nicotinamide N-methyltransferase (NNMT) is a cytosolic enzyme that catalyzes the methylation of nicotinamide using S-adenosylmethionine (SAM) as a methyl donor, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine (SAH)

The B12 component may help counteract this

Most individuals obtain sufficient B12 from a balanced diet containing meat, fish, dairy products, and fortified foods

What can go wrong Pain, swelling and a small lump The most common outcome of a rushed or badly angled injection is local irritation: soreness, redness, a small firm lump or a bruise