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Elevated hsCRP is an independent cardiovascular risk factor, and its reduction is considered a surrogate marker for improved cardiovascular outcomes Systolic blood pressure clinically meaningful reductions These improvements are consistent with but in several cases exceed the cardiometabolic benefits observed with semaglutide and tirzepatide in their respective Phase III programs

Altintas UB, Seo JH, Giambartolomei C, Ozturan D, Fortunato BJ, Nelson GM, et al

Additionally, high doses of AOXs may be associated with some adverse effects

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