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One additional challenge is identifying specific and reliable markers that are exclusively expressed on senescent cells to ensure accurate targeting by CAR-T cells or antibodies or to use for immunization

Cosmetic response varies

The histological analysis was performed using a high power objective (x63) in the microscope ZEISS AXIOSKOP 2, by counting cells in three areas with a minimum of approximately 100 m 2 , using three distinct serial sections (50 m interval between sections) per animal, for five different animals

Fibroids are responsible for about one-third of all hysterectomies (4, 5)