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These compounds sit in a gray zone: they are legal to sell and own for laboratory research, but they are not approved by the FDA for human use and are not dietary supplements

For conditions like melasma that inherently require long-term management, this creates a cycle that is difficult to break without clinical supervision

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Methods Study Population Between November 1996 and December 1997, 732 patients referred to the Department of Medicine II of the Johannes Gutenberg University in Mainz, Germany, with suspected coronary artery disease were enrolled in the AtheroGene registry

Conclusion While glutathione supplements are not FDA-approved in the same way as prescription drugs, they are subject to regulatory oversight under the dietary supplement framework