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Warnings Benzyl Alcohol Patients who have early Leber's disease (LHON) a hereditary disease that causes optic nerve atrophy have been found to suffer severe and swift optic atrophy when treated with vitamin B12

This triggers downstream signaling pathways (e.g., NF-B and MAPK), driving the massive release of pro-inflammatory cytokines, including IL-1, IL-6, and TNF- (167170)

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In the past many companies created simple coatings that provided a brief comfort to the user's gut and only a small amount of usable ingredients making its way into the bloodstream