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In, Kaplowitz N, DeLeve LD, eds

These medications are usually taken as weekly injectables, but Rybelsus and more recently, Wegovy is available as a once-daily pill

Inhibition of autophagy in microglia and macrophages exacerbates innate immune responses and worsens brain injury outcomes

Prior to the development of FOXO4-DRI, research into cellular senescence largely relied on indirect markers of aging, generalized apoptosis pathways, or broad-spectrum senolytic compounds