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[1] [3] Pregnancy and lactation are additional considerations, as tirzepatide has shown embryo-fetal risk in animal studies and is not recommended during pregnancy or breastfeeding

It was originally studied for its gastroprotective effects , with researchers exploring its potential to heal stomach ulcers

Luminal glucose represents the most potent secretagogue for incretin hormone release in vivo , an effect mainly mediated by the sodium-dependent glucose transporter, SGLT1 (SLC5A1) (15)

In vitro experiments have demonstrated that asparagus extract can alleviate TMAO-induced endothelial dysfunction, and the mechanism may be related to improving the TMAO-induced decrease in EC proliferation and regulating the molecular circadian clock controlled by NEAT1 and MAPK signaling pathways

Tablets, however, are considered safe for daily use when approved by regulatory authorities like FSSAI