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Use: To reduce the risk of sustained estimated eGFR decline, ESRD, and CV death in patients with type 2 diabetes mellitus and chronic kidney disease Usual Adult Dose for Metabolic Dysfunction-Associated Steatohepatitis Wegovy injection: Initial dose (weeks 1 through 4): 0.25 mg subcutaneously once a week Dose escalation: Weeks 5 through 8: 0.5 mg subcutaneously once a week Weeks 9 through 12: 1 mg subcutaneously once a week Weeks 13 through 16: 1.7 mg subcutaneously once a week If 2.4 mg is not tolerated: 1.7 mg subcutaneously once a week

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For example, a 2025 study in the Journal of the American Medical Association (JAMA) found people taking Ozempic were about 1.8 times as likely to experience vision loss from NAION, than those prescribed other diabetes medications