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Risk of bias assessment Four authors independently assessed the risk of bias (RoB) using version 2 of the Cochrane RoB tool for randomized trials (RoB 2) within the Review Manager (RevMan) computer program, version 7.2.0 (Cochrane Collaboration, London, UK) [20,21]

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They are not medicines, not for human consumption, and not a substitute for an MHRA-authorised prescription product obtained via a registered UK prescriber

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