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Gloyn noted that large amounts of genetic data from clinical trials likely already exist and could help answer important questions about why some people respond poorly to GLP-1 therapies

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Neurodegener Dis 9(3):107120 Sun H, Knippenberg S, Thau N, Ragancokova D, Krner S, Huang D, Dengler R, Dhler K, Petri S (2013) Therapeutic potential of N-acetyl-glucagon-like peptide-1 in primary motor neuron cultures derived from non-transgenic and SOD1-G93A ALS mice

P = .001) and 6 months (7.2% vs

The impact of INSL-5 on glucose control in mice also appears dependent on the mode of glucose delivery, as blood glucose or insulin levels were similar in Insl5 / mice compared to WT following an oral glucose test (164, 168)